In-Situ CIP-SIP System
CIP-SIP System
At Esteril Process Solutions, we design and manufacture advanced Cleaning-In-Place (CIP) and Sterilization-In-Place (SIP) systems for automated cleaning, sanitization, and sterilization of pharmaceutical process equipment and piping systems.
Our modular skid-mounted CIP/SIP systems are engineered to provide efficient and repeatable cleaning cycles for fixed process equipment, multi-tank systems, and aseptic manufacturing setups. Available in fully automated and semi-automated configurations, these systems are customized based on process requirements and production capacities.
Designed for modern multiproduct pharmaceutical facilities, our systems ensure effective contamination control, process consistency, and regulatory compliance.
APPLICATIONS
Suitable for cleaning and sterilization of:
- Manufacturing vessels and holding tanks
- Process piping systems
- Bioreactors and fermenters
- Filtration and transfer systems
- Aseptic pharmaceutical processing equipment
ADVANTAGES
- Compact skid-mounted design with no separate installation required
- Custom-designed systems based on product flow requirements
- Heating and cooling integration options
- Reliable full / semi-automated operation
- Tailor-made solutions for custom applications
- Reduced manual intervention and improved process efficiency
KEY FEATURES
- Sanitary design as per US FDA / cGMP / ASME-BPE standards
- SS 316L contact parts with mirror & electro-polished finish
- SS 304 non-contact parts with matt finish
- Hygienic orbital tube welding
Online acid and alkaline dosing provision - SS 304 polished skid structure
- Sanitary moisture separator and pressure regulating valve
- Automation compliant with USFDA 21 CFR Part 11
- Cleaning validation capability with Riboflavin Test
- Bottom-mounted magnetic mixers with low / medium / high shear options
- Flexible recipe-based process parameter settings
- Sterile flange connections
- Load cells / level sensors for accurate monitoring
